Study is a double-blind, randomized, placebo controlled, dose escalating study. The purpose of this post-marketing study is to compare the safety of tofacitinib versus tumor necrosis factor inhibitor with respect to major cardiovascular adverse events and malignancies, excluding non-melanoma skin cancers, when given to subjects with rheumatoid arthritis. Other safety events, including non-melanoma skin cancers, hepatic events, infections, and effectiveness parameters will be collected and evaluated in the study.
Corticosteroid injections are commonly used for the symptomatic treatment of knee osteoarthritis. Common practice is to inject the joint with a combination of corticosteroid and local anesthetic, with the rationale of providing longer duration pain relief with the corticosteroid and immediate, though short duration relief with the anesthetic.
However, multiple in vitro and animal studies have shown that local anesthetic may be harmful to chondrocytes. Despite this data, use of intra-articular anesthetic remains widespread. Many clinicians believe incorporating the anesthetic is important because it can provide immediate pain relief and facilitate patient confidence in the treatment program.
However, there is The purpose of this study is to assess and compare regenerative injection therapies such as bone marrow aspiration and concentration BMAC and platelet rich plasma PRP for osteoarthritis. The purpose of this study is to determine if a treatment based on the combination of platelet rich plasma and HA obtained with the A-CP HA Kit is statistically superior to a saline placebo or HA alone in terms of Improvement of OA-related symptoms between baseline D0 and Month 6, and reduction of pain at walking between baseline D0 and Month 6.
This study aims to compare postoperative pain levels between three 3 treatment groups, using the Numerical Rating Scale NRS. Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases.
In particular, this observational registry will be used to answer pressing questions about therapeutics used to treat pediatric rheumatic diseases, including safety questions. Patients with active Axial Spondyloarthritis without x-ray evidence of Ankylosing Spondylitis and with signs of inflammation will be randomly assigned to receive certolizumab pegol CZP mg every two weeks or placebo.
The primary objective is to demonstrate the efficacy of CZP in these patients. The purpose of this study is to establish a comparator cohort of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and other spondyloarthropathies. We will collect demographic information, historical information about diagnosis and past treatment, and clinical, radiographic, and laboratory data on each patient using standardized data collection forms.
We will also collect blood and synovial tissue samples from each patient. Not only are we raising awareness of clinical trials to the arthritis community, we will also increase participation — which we hope will encourage more research and innovation. Are you ready to start using the Finder? You have the option to add other filters and keywords to your search. I am looking for leflunomide.
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The purpose of this study is to observe radiographic outcomes of patients who will undergo anterior cervical discectomy and fusion ACDF utilizing Tritanium C Stryker Spine. The rate of fusion success and adverse events will be compared retrospectively to patients who underwent instrumented ACDF utilizing structural allograft bone with plates. This study will evaluate if there is a difference in recovery of tendon structure and mechanical properties between males and females with Achilles tendinopathy receiving exercise treatment.
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